Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis
By Rolando E. Rumbaut

, 75 pages © 2010
ISBN 1615040390
Availability: Available
Price: US $30.00 Add to Cart

Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.
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